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Results: GHK-Cu alleviated weight loss, improved the disease activity index (DAI), reduced colonic edema and shortening, attenuated inflammatory damage, increased goblet cell numbers, suppressed inflammatory cytokines such as TNF-, IL-6, and IL-1, and promoted mucosal repair

The K7M2 cells were maintained in DMEM, also supplemented with 10% FBS and 1% P/S

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This anatomical specificity may explain nicotines differential regulation of distinct behavioral paradigms ( 7 homomeric nAChRs play a relatively limited role in nicotine rewarding mechanisms